Also, MAKE SURE to set Mode (in the bottom left corner of the options menu) to “Windowed”.
Make sure to go to options on the launcher and set your graphics to High or Ultra, depending on what your system can handle. You MUST follow everything exactly as it is written or you will cause massive headaches for yourself. Similar to my oblivion mod guide, my goal is mostly to make the game look better while keeping the gameplay as close to vanilla as possible (with few exceptions). Here’s a list/guide on the Fallout New Vegas mods that I am using and how to install them.